LITERATURE · PEER REVIEWED

Role of Ash1l in Tourette syndrome and other neurodevelopmental disorders

Developmental Neurobiology · 2021 · Peer reviewed

COMPLETE CITATION

Citation and identifiers

Zhang C, et al.. “Role of Ash1l in Tourette syndrome and other neurodevelopmental disorders.” Developmental Neurobiology. 81(2):79–91 · doi:10.1002/dneu.22795.

PubMed ID
33258273

RESEARCH QUESTION

How do ASH1L genetics and model findings relate across Tourette syndrome, autism, and intellectual disability?

This narrative review compares ASH1L evidence across several neurodevelopmental contexts without establishing that their ascertainment, mechanisms, or clinical phenotypes are interchangeable.

INTERPRETATION BOUNDARY

Read the finding and limit together.

What this study supports

Reviews ASH1L genetics and model biology across Tourette syndrome, autism, and intellectual disability.

What it cannot establish

Narrative synthesis; disease contexts and variant mechanisms should not be merged into one clinical phenotype.

OPEN THE STUDY