COMPLETE CITATION
Citation and identifiers
Liu H, Liu D-T, Lan S, et al.. “ASH1L mutation caused seizures and intellectual disability in twin sisters.” Journal of Clinical Neuroscience. 91:69–74 · doi:10.1016/j.jocn.2021.06.038.
- PubMed ID
- 34373061 ↗
RESEARCH QUESTION
What do ASH1L-associated seizures and intellectual disability in twin sisters show about inheritance and within-family phenotypic comparison?
The twin report supports a within-family clinical comparison, but the related individuals are not independent recurrence events and cannot establish penetrance.
INTERPRETATION BOUNDARY
Read the finding and limit together.
What this study supports
Twin report relevant to epilepsy, inheritance, and within-family phenotypic comparison.
What it cannot establish
Related individuals are not independent recurrence events and cannot establish penetrance.
OPEN THE STUDY