COMPLETE CITATION
Citation and identifiers
Tanaka Y, Katagiri Z, Kawahashi K, et al.. “Dual function of histone H3 lysine 36 methyltransferase ASH1 in regulation of Hox gene expression.” PLOS ONE. 6(11):e28171 · doi:10.1371/journal.pone.0028171.
- PubMed ID
- 22140534 ↗
RESEARCH QUESTION
How does ASH1L contribute to Hox gene regulation through H3K36 methyltransferase-linked chromatin activity?
The study supplies foundational gene-regulation evidence from a non-neurodevelopmental setting rather than direct evidence about human phenotype.
INTERPRETATION BOUNDARY
Read the finding and limit together.
What this study supports
Historically Yale-affiliated molecular work examining ASH1L-dependent Hox regulation and chromatin function.
What it cannot establish
Foundational gene-regulation evidence from a non-neurodevelopmental context; not human phenotype evidence.
OPEN THE STUDY