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Best match: The words should help—not become another barrier.H3K36 Also searched as: histone H3 lysine 36 · H3K36 methylation · H3K36me2 A position on histone H3 that can carry methyl marks involved in chromatin regulation; ASH1L has H3K36 methyltransferase activity in experimental systems.
Open result PageBiology · BiologyWhere ASH1L has been experimentally perturbed—not merely detected.
Best match: 13 source-linked models, with every model boundary visible., 2022 ↗ Heart development Drosophila cardiac tissue · Distal in vivo model Ash1 with Caf1-55 and MRG15 supported H3K36me2-dependent heart development in vivo.
Open result PageBiology · BiologyKeep the model, assay, and evidence limit attached.
Best match: Primary mechanistic evidence…models H3K36-modified nucleosomes and selected Ash1l-dependent loci H3K36me2/3 on the same nucleosome inhibited PRC2 H3K27 methylation; Ash1l opposed Polycomb at selected loci.
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