COMPLETE CITATION
Citation and identifiers
Yu M, Jia Y, Ma Z, et al.. “Structural insight into ASH1L PHD finger recognizing methylated histone H3K4 and promoting cell growth in prostate cancer.” Frontiers in Oncology. 12:906807 · doi:10.3389/fonc.2022.906807.
- PubMed ID
- 36033518 ↗
RESEARCH QUESTION
How does the ASH1L PHD finger recognize methylated histone H3K4 in the studied prostate-cancer context?
The structural work characterizes PHD-finger recognition of histone tails and associated cell growth in cancer without supporting a clinical inference for ASH1L-related neurodevelopmental disorder.
INTERPRETATION BOUNDARY
Read the finding and limit together.
What this study supports
Provides structural information about the PHD finger and histone-tail recognition.
What it cannot establish
Cancer context; it does not support a clinical inference for ASH1L-related neurodevelopmental disorder.
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