COMPLETE CITATION
Citation and identifiers
Jones M, Chase J, Xu J, et al.. “ASH1L controls quiescence and self-renewal potential in hematopoietic stem cells.” Journal of Clinical Investigation. 125(5):2007–2020 · doi:10.1172/JCI78124.
- PubMed ID
- 25866973 ↗
RESEARCH QUESTION
How does ASH1L regulate quiescence and self-renewal in hematopoietic stem cells?
The hematopoietic stem-cell mechanism provides direct blood-lineage biology but is not evidence of a blood or immune manifestation in ASH1L-related neurodevelopmental disorder.
INTERPRETATION BOUNDARY
Read the finding and limit together.
What this study supports
Establishes an ASH1L role in hematopoietic stem-cell quiescence and self-renewal.
What it cannot establish
Mechanistic tissue context, not evidence of a blood or immune manifestation in an individual with ASH1L-related NDD.
OPEN THE STUDY