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3 results for “myelination”

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Page · Biology

Tissue & cell biology

Best match: Where ASH1L has been experimentally perturbed—not merely detected.

…ESTABLISHES Ash1l loss altered cortical development, progenitor programs, myelination, growth, and later behavioral and memory measures in the tested model.

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Evidence library

Best match: 2021 Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors Gao Y, Duque-Wilckens N, Aljazi MB, et al. · Communications Biology Peer reviewed

He Lab / MSU Question this source can answer: How does developmental neural-lineage loss of Ash1l affect cortical development, myelination, cognition, and behavior in mice?

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Program & purpose

Best match: Human questions translated into testable biology.

01 · PUBLISHED MODEL Developmental gene regulation Neural-lineage Ash1l loss in mice altered developmental gene programs, cortical development, myelination, and later cognitive and behavioral measures.

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